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EAWAG 2007

| ESBS | ETH/UZH
IBT, Wädenswil
ITC, Prague
VIB DMBR, Ghent
TU, Graz

ESBS:

Date kBDocumentType
17  10.05.07   HSW 11075 Simulation tutorial 2007 doc
16  03.05.07   HSW 202 How to check your Java Version doc
15  02.03.07   HSW 973 BiotechSIM Architecture doc
14  02.03.07   HSW 157 Description of how to use SIM offline doc
13  02.03.07   HSW 1397 Sim Applet for offline use zip
12  27.02.07   Eawag 357 BiotechSIM Kurzanleitung 2007 doc
11  27.02.07   HSW 838 Simulation tutorial 2006 pdf
10  26.02.07   HSW 1 Scenario:ESBS Continuous Solutions tpars
18.02.07   HSW 46 Lösungen: Kontinuierliche Kultur ? Chemostat doc
16.02.07   HSW 36 Lösungen: Kontinuierliche Kultur - Störung des steady-states doc
16.02.07   HSW 46 Lösungen: Batchkultur - Wachstum und Limitation doc
13.02.07   HSW 2 Unterlagen für Übung 4A zip
12.02.07   EAWAG ? Steady state doc
12.02.07   EAWAG ? Kinetics doc
12.02.07   EAWAG ? Chemostat doc
12.02.07   EAWAG ? Batchwachstum doc
09.02.07   EAWAG 176 Gleichungen doc
 
ETH/UZH:

Date kBDocumentType
11  05.10.07   HSW 235 Simulation Chemostat xls
10  05.10.07   EAWAG 16 Topic 2: Data Kaysser et al. 2005 xls
05.10.07   EAWAG 22 Topic 2: Data Ihssen and Egli 2004 xls
05.10.07   EAWAG 16 Topic 1: Data Varma and Palsson (1994) xls
05.10.07   HSW 235 Simulation Chemostat_english xls
04.10.07   EAWAG ? Topic 2: Continuous culture ? x(t), s(t) graphs versus x(D), s(D) diagrams doc
04.10.07   EAWAG ? Topic 6: Transients ? Interpretation of the experimental data doc
04.10.07   EAWAG ? Topic 5: Continuous culture - interpretation of experimental data doc
04.10.07   EAWAG ? Topic 4: Batch growth - interpretation of experimental data doc
04.10.07   EAWAG ? Topic 3: Transition from batch to continuous culture doc
04.10.07   EAWAG ? Topic 1: Batch-Growth doc
 


 
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References



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Blank, L. M. 1997. Molecular and fermentation characterization of recombinant strains for metabolic engineering studies of Clostridium acetobutylicum. Master Thesis. Northwestern University, Evanston, IL, USA.
Cereghino, J.L., and J.M. Cregg. 2000. Heterologous protein expression in the methylotrophic yeast Pichia pastoris. FEMS Microbiol. Rev. 24: 45-66.
483 kBpdf
Curvers, S., P. Brixius, T. Klauser, J. Thoemmes, B.D. Weuster, R. Takors, and C. Wandrey. 2001. Human chymotrypsinogen B production with Pichia pastoris by integrated development of fermentation and downstream processing. Part 1. Fermentation. Biotechnol. Prog. 17: 495-502.
213 kBpdf
d’Anjou, M.C., and A.J. Daugulis. 2001. A rational approach to improving productivity in recombinant Pichia pastoris fermentation. Biotechnol. Bioeng. 72: 1–11.
214 kBpdf
Desai, R.P., L.K. Nielsen, and E.T. Papoutsakis. 1999. Stoichiometric modeling of Clostridium acetobutylicum fermentations with non-linear constraints. J. Biotechnol. 71:191-205.
230 kBpdf
Egli, T., Bosshard, C., and G. Hamer. 1986. Simultaneous utilization of methanol-glucose mixtures by Hansenula polymorpha in chemostat: Influence of dilution rate and mixture composition on utilization pattern. Biotechnol. Bioneng. 28: 1734-1741.
903 kBpdf
Egli, T., J.P. van Dijken, M. Veenhuis, W. Harder, and A. Fiechter. 1980. Methanol Metabolism in Yeasts: Regulation of the Synthesis of Catabolic Enzymes. Arch. Microbiol. 124: 115-121.
1777 kBpdf
Hans-Peter Meyer, 7. Juni 2007
1307 kBpdf
Harris, L.M., L. Blank, R.P. Desai, N.E. Welker, and E.T. Papoutsakis. 2001. Fermentation characterization and flux analysis of recombinant strains of Clostridium acetobutylicum with an inactivated solR gene. J. Ind. Microbiol. Biotechnol. 27: 322-328.
167 kBpdf
Ihssen, J., and T. Egli. 2004. Specific growth rate and not cell density controls the general stress response in Escherichia coli. Microbiol. 150: 1637 – 1648.
319 kBpdf
Invitrogen. 2002. Pichia Fermentation Process Guidelines. Catalog No. K1710-01, Version B 053002, 1-11. http://www.invitrogen.com/content/sfs/manuals/pichiaferm_prot.pdf
162 kBpdf
Kayser, A., J. Weber, V. Hecht, and U. Rinas. 2005. Metabolic flux analysis of Escherichia coli in glucose-limited continuous culture. I. Growth-rate-dependent metabolic efficiency at steady state. Microbiol. 151: 693 - 706.
226 kBpdf
Kovářová, K., A.J.B. Zehnder, and T. Egli. 1996. Temperature-Dependent Growth Kinetics of Escherichia coli ML 30 in Glucose-Limited Continuous Culture. J. Bacteriol. 178: 4530-4539.
340 kBpdf
Kovarova-Kovar, K., and T. Egli. 1998. Growth Kinetics of Suspended Microbial cells: From Single-Substrate-Controlled Growth to Mixed-Substrate Kinetics. Microbiol. Mol. Biol. Rev. 62: 646–666.
2980 kBpdf
Lendenmann, U., H. Senn, M. Snozzi, and T. Egli. 2000. Dynamics of Mixed Substrate Growth of Escherichia coli in Batch Culture: the Transition between Simultaneous and Sequential Utilisation of Carbon Substrates. Acta Univ. Carol. Environ. 14: 21-31.
2509 kBpdf
Maurer, M., M., Kühleitner, B. Gasser, and D. Mattanovich. 2006. Versatile modeling adn optimization of fed  batch processes for the production of secreted heterologous proteins with Pichia pastoris. Microbial Cell Factories. 5: 37.
323 kBpdf
Minning, S., A. Serrano, P. Ferrer, C. Solá, R.D. Schmid, and F. Valero. 2001. Optimization of the high-level production of Rhizopus oryzae lipase in Pichia pastoris. J. Biotechnol. 86: 59–70.
196 kBpdf
Monod, J. 1949.The growth of bacterial cultures. Annu. Rev. Microbiol. 3: 371-394.
1380 kBpdf
Papoutsakis, E.T. 1984. Equations and Calculations for Fermentations of Butyric Acid Bacteria. Biotechnol. Bioeng. XXVI: 174-187.
1295 kBpdf
Piñar, G., K. Kovářová, T. Egli, and J.L. Ramos. 1998. Influence of Carbon Source on Nitrate Removal by Nitrate tolerant Klebsiella oxytoca CECT 4460 in Batch and Chemostat Cultures. Appl. Env. Microbiol. 64: 2970 - 2976. 
2073 kBpdf
Standing, C.N., A.G. Frederickson, and H.M. Tschuchiya. 1972. Batch and continuous-culture transients for two substrate systems. Appl. Microbiol. 23: 354-359.
699 kBpdf
Tao, H., C. Bausch, C. Richmond, F.R. Blattner, and T. Conway. 1999. Functional Genomics: Expression Analysis of Escherichia coli. Growing on Minimal and Rich Media. J. Bacteriol. 181: 6425 - 6440.
1787 kBpdf
van Dijken, J.P., Otto, R., and W. Harder. 1976. Growth of Hansenula polymorpha in a methanol-limited chemostat. Arch. Microbiol. 111: 137-144.
1375 kBpdf
Varma, A., and B.O. Palsson. 1994. Stoichiometric Flux Balance Models Quantitatively Predict Growth and Metabolic By-Product Secretion in Wild-Type Escherichia coli W3110. Appl. Environ. Microbiol. 60: 3724-3731.
1398 kBpdf
von Meyenburg, K. 1971. Transport-Limited Growth Rates in a Mutant of Escherichia coli. J. Bacteriol. 107: 878-888.
1371 kBpdf
Wanner, U., and T. Egli. 1990. Dynamics of microbial growth and cell composition in batch culture. FEMS Microbiol. Rev. 75: 19-44.
3208 kBpdf
Zhang, W., J. Sinha, L. A. Smith, M. Inan, and M.M. Meagher. 2005. Maximization of production of secreted recombinant proteins in Pichia pastoris fed batch fermentation. Biotechnol. Prog. 21: 386-393.
195 kBpdf
 
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